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BMCBI
2010
13 years 6 months ago
2010
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
BMCBI
2010
13 years 6 months ago
2010
Background: The recognition of functional binding sites in genomic DNA remains one of the fundamental challenges of genome research. During the last decades, a plethora of differe...
BMCBI
2005
13 years 6 months ago
2005
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
SIGMOD
2003
ACM
14 years 6 months ago
2003
ACM
The Aurora system [1] is an experimental data stream management system with a fully functional prototype. It includes both a graphical development environment, and a runtime syste...
BMCBI
2008
13 years 6 months ago
2008
Background: Significance analysis at single gene level may suffer from the limited number of samples and experimental noise that can severely limit the power of the chosen statist...