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» A scalable algorithm for clustering protein sequences
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BMCBI
2010
160views more  BMCBI 2010»
13 years 8 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
BMCBI
2005
147views more  BMCBI 2005»
13 years 7 months ago
GATA: a graphic alignment tool for comparative sequence analysis
Background: Several problems exist with current methods used to align DNA sequences for comparative sequence analysis. Most dynamic programming algorithms assume that conserved se...
David A. Nix, Michael B. Eisen
CF
2009
ACM
14 years 2 months ago
Quantitative analysis of sequence alignment applications on multiprocessor architectures
The exponential growth of databases that contains biological information (such as protein and DNA data) demands great efforts to improve the performance of computational platforms...
Friman Sánchez, Alex Ramírez, Mateo ...
BMCBI
2008
141views more  BMCBI 2008»
13 years 8 months ago
The development of PIPA: an integrated and automated pipeline for genome-wide protein function annotation
Background: Automated protein function prediction methods are needed to keep pace with high-throughput sequencing. With the existence of many programs and databases for inferring ...
Chenggang Yu, Nela Zavaljevski, Valmik Desai, Seth...
RECOMB
2002
Springer
14 years 8 months ago
Probabilistic hierarchical clustering for biological data
Biological data, such as gene expression profiles or protein sequences, is often organized in a hierarchy of classes, where the instances assigned to "nearby" classes in...
Eran Segal, Daphne Koller