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» A scalable algorithm for clustering protein sequences
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BMCBI
2006
110views more  BMCBI 2006»
13 years 8 months ago
Design of a combinatorial DNA microarray for protein-DNA interaction studies
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...
Julian Mintseris, Michael B. Eisen
ISMB
1994
13 years 9 months ago
Predicting Location and Structure Of beta-Sheet Regions Using Stochastic Tree Grammars
We describe and demonstrate the effectiveness of a method of predicting protein secondary structures, sheet regions in particular, using a class of stochastic tree grammars as rep...
Hiroshi Mamitsuka, Naoki Abe
BMCBI
2005
92views more  BMCBI 2005»
13 years 7 months ago
Predicting functional sites with an automated algorithm suitable for heterogeneous datasets
Background: In a previous report (La et al., Proteins, 2005), we have demonstrated that the identification of phylogenetic motifs, protein sequence fragments conserving the overal...
David La, Dennis R. Livesay
BMCBI
2004
95views more  BMCBI 2004»
13 years 7 months ago
PCOGR: Phylogenetic COG ranking as an online tool to judge the specificity of COGs with respect to freely definable groups of or
Background: The rapidly increasing number of completely sequenced genomes led to the establishment of the COG-database which, based on sequence homologies, assigns similar protein...
Florian Meereis, Michael Kaufmann
NAR
2008
138views more  NAR 2008»
13 years 7 months ago
TarO: a target optimisation system for structural biology
TarO (http://www.compbio.dundee.ac.uk/taro) offers a single point of reference for key bioinformatics analyses relevant to selecting proteins or domains for study by structural bi...
Ian M. Overton, C. A. Johannes van Niekerk, Lester...