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BIBE
2006
IEEE
119views Bioinformatics» more  BIBE 2006»
14 years 1 months ago
Large Grain Size Stochastic Optimization Alignment
DNA sequence alignment is a critical step in identifying homology between organisms. The most widely used alignment program, ClustalW, is known to suffer from the local minima pro...
Perry Ridge, Hyrum Carroll, Dan Sneddon, Mark J. C...
CDC
2009
IEEE
147views Control Systems» more  CDC 2009»
14 years 6 days ago
A simulation-based method for aggregating Markov chains
— This paper addresses model reduction for a Markov chain on a large state space. A simulation-based framework is introduced to perform state aggregation of the Markov chain base...
Kun Deng, Prashant G. Mehta, Sean P. Meyn
CSB
2004
IEEE
208views Bioinformatics» more  CSB 2004»
13 years 11 months ago
Pair Stochastic Tree Adjoining Grammars for Aligning and Predicting Pseudoknot RNA Structures
Motivation: Since the whole genome sequences for many species are currently available, computational predictions of RNA secondary structures and computational identifications of t...
Hiroshi Matsui, Kengo Sato, Yasubumi Sakakibara
IPCO
2004
107views Optimization» more  IPCO 2004»
13 years 9 months ago
A Robust Optimization Approach to Supply Chain Management
Abstract. We propose a general methodology based on robust optimization to address the problem of optimally controlling a supply chain subject to stochastic demand in discrete time...
Dimitris Bertsimas, Aurélie Thiele
AMAI
2008
Springer
13 years 7 months ago
Bayesian learning of Bayesian networks with informative priors
This paper presents and evaluates an approach to Bayesian model averaging where the models are Bayesian nets (BNs). Prior distributions are defined using stochastic logic programs...
Nicos Angelopoulos, James Cussens