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» A stable gene selection in microarray data analysis
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BMCBI
2011
13 years 2 months ago
SNP-based pathway enrichment analysis for genome-wide association studies
Background: Recently we have witnessed a surge of interest in using genome-wide association studies (GWAS) to discover the genetic basis of complex diseases. Many genetic variatio...
Lingjie Weng, Fabio Macciardi, Aravind Subramanian...
JRTIP
2006
114views more  JRTIP 2006»
13 years 7 months ago
Sensor band selection for multispectral imaging via average normalized information
The information-rich scene descriptors created by multispectral sensors can act as a bottleneck in further analysis. Many of the spectral band selection methods treat the two under...
Hongzhi Wang, Elli Angelopoulou
BMCBI
2010
114views more  BMCBI 2010»
13 years 7 months ago
An integrative modular approach to systematically predict gene-phenotype associations
Background: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these com...
Michael R. Mehan, Juan Nunez-Iglesias, Chao Dai, M...
BMCBI
2008
138views more  BMCBI 2008»
13 years 7 months ago
Methods for simultaneously identifying coherent local clusters with smooth global patterns in gene expression profiles
Background: The hierarchical clustering tree (HCT) with a dendrogram [1] and the singular value decomposition (SVD) with a dimension-reduced representative map [2] are popular met...
Yin-Jing Tien, Yun-Shien Lee, Han-Ming Wu, Chun-Ho...
BMCBI
2010
149views more  BMCBI 2010»
13 years 7 months ago
Identifying common prognostic factors in genomic cancer studies: A novel index for censored outcomes
Background: With the growing number of public repositories for high-throughput genomic data, it is of great interest to combine the results produced by independent research groups...
Sigrid Rouam, Thierry Moreau, Philippe Broët