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» A stable gene selection in microarray data analysis
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BMCBI
2008
138views more  BMCBI 2008»
13 years 8 months ago
Combining transcriptional datasets using the generalized singular value decomposition
Background: Both microarrays and quantitative real-time PCR are convenient tools for studying the transcriptional levels of genes. The former is preferable for large scale studies...
Andreas W. Schreiber, Neil J. Shirley, Rachel A. B...
BMCBI
2005
126views more  BMCBI 2005»
13 years 7 months ago
Integrative analysis of multiple gene expression profiles with quality-adjusted effect size models
Background: With the explosion of microarray studies, an enormous amount of data is being produced. Systematic integration of gene expression data from different sources increases...
Pingzhao Hu, Celia M. T. Greenwood, Joseph Beyene
BMCBI
2006
117views more  BMCBI 2006»
13 years 8 months ago
Analysis of gene expression changes in relation to toxicity and tumorigenesis in the livers of Big Blue transgenic rats fed comf
Background: Comfrey is consumed by humans as a vegetable and a tea, and has been used as an herbal medicine for more than 2000 years. Comfrey, however, is hepatotoxic in livestock...
Nan Mei, Lei Guo, Lu Zhang 0013, Leming M. Shi, Yo...
BIBM
2008
IEEE
108views Bioinformatics» more  BIBM 2008»
14 years 2 months ago
Systematic Evaluation of Scaling Methods for Gene Expression Data
Even after an experimentally prepared gene expression data set has been pre-processed to account for variations in the microarray technology, there may be inconsistencies between ...
Gaurav Pandey, Lakshmi Naarayanan Ramakrishnan, Mi...
RECOMB
2008
Springer
14 years 8 months ago
Detecting Disease-Specific Dysregulated Pathways Via Analysis of Clinical Expression Profiles
We present a method for identifying connected gene subnetworks significantly enriched for genes that are dysregulated in specimens of a disease. These subnetworks provide a signat...
Igor Ulitsky, Richard M. Karp, Ron Shamir