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» A statistical approach for array CGH data analysis
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BMCBI
2010
165views more  BMCBI 2010»
13 years 7 months ago
Filtering, FDR and power
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
Maarten van Iterson, Judith M. Boer, Renée ...
BMCBI
2008
129views more  BMCBI 2008»
13 years 7 months ago
A unified approach to false discovery rate estimation
Background: False discovery rate (FDR) methods play an important role in analyzing highdimensional data. There are two types of FDR, tail area-based FDR and local FDR, as well as ...
Korbinian Strimmer
BMCBI
2006
142views more  BMCBI 2006»
13 years 7 months ago
PedGenie: an analysis approach for genetic association testing in extended pedigrees and genealogies of arbitrary size
Background: We present a general approach to perform association analyses in pedigrees of arbitrary size and structure, which also allows for a mixture of pedigree members and ind...
Kristina Allen-Brady, Jathine Wong, Nicola J. Camp
CORR
2010
Springer
108views Education» more  CORR 2010»
13 years 7 months ago
Mining The Successful Binary Combinations: Methodology and A Simple Case Study
The importance of finding the characteristics leading to either a success or a failure is one of the driving forces of data mining. The various application areas of finding succes...
Yuval Cohen
BIB
2010
89views more  BIB 2010»
13 years 6 months ago
Knowledge-based data analysis comes of age
The emergence of high-throughput technologies for measuring biological systems has introduced problems for data interpretation that must be addressed for proper inference. First, ...
Michael F. Ochs