Background: Chromatin immunoprecipitation followed by microarray hybridization (ChIP-chip) is used to study protein-DNA interactions and histone modifications on a genome-scale. T...
Background: DNA copy number aberration (CNA) is very important in the pathogenesis of tumors and other diseases. For example, CNAs may result in suppression of anti-oncogenes and ...
We present a new statistically optimal approach to estimate transcript levels and ratios from one or more gene array experiments. The Bayesian Estimation of Array Measurements (BE...
Ron O. Dror, Jonathan G. Murnick, Nicola A. Rinald...
The problem of maintaining efficiently a large number (say millions) of statistics counters that need to be updated at very high speeds (e.g. 40 Gb/s) has received considerable re...
Haiquan (Chuck) Zhao, Hao Wang, Bill Lin, Jun (Jim...
Analysis of postgenomic biological data (such as microarray and SNP data) is a subtle art and science, and the statistical methods most commonly utilized sometimes prove inadequat...