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COMPLIFE
2006
Springer
13 years 11 months ago
Beating the Noise: New Statistical Methods for Detecting Signals in MALDI-TOF Spectra Below Noise Level
Background: The computer-assisted detection of small molecules by mass spectrometry in biological samples provides a snapshot of thousands of peptides, protein fragments and prote...
Tim O. F. Conrad, Alexander Leichtle, Andre Hageh&...
BMCBI
2008
153views more  BMCBI 2008»
13 years 7 months ago
AWclust: point-and-click software for non-parametric population structure analysis
Background: Population structure analysis is important to genetic association studies and evolutionary investigations. Parametric approaches, e.g. STRUCTURE and L-POP, usually ass...
Xiaoyi Gao, Joshua D. Starmer
GECCO
2007
Springer
256views Optimization» more  GECCO 2007»
14 years 1 months ago
A particle swarm optimization approach for estimating parameter confidence regions
Point estimates of the parameters in real world models convey valuable information about the actual system. However, parameter comparisons and/or statistical inference requires de...
Praveen Koduru, Stephen Welch, Sanjoy Das
BMCBI
2006
86views more  BMCBI 2006»
13 years 7 months ago
Identification of QTLs controlling gene expression networks defined a priori
Background: Gene expression microarrays allow the quantification of transcript accumulation for many or all genes in a genome. This technology has been utilized for a range of inv...
Daniel J. Kliebenstein, Marilyn A. L. West, Hans v...
BMCBI
2010
120views more  BMCBI 2010»
13 years 7 months ago
Modeling expression quantitative trait loci in data combining ethnic populations
Background: Combining data from different ethnic populations in a study can increase efficacy of methods designed to identify expression quantitative trait loci (eQTL) compared to...
Ching-Lin Hsiao, Ie-Bin Lian, Ai-Ru Hsieh, Cathy S...