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CSB
2004
IEEE
208views Bioinformatics» more  CSB 2004»
13 years 11 months ago
Pair Stochastic Tree Adjoining Grammars for Aligning and Predicting Pseudoknot RNA Structures
Motivation: Since the whole genome sequences for many species are currently available, computational predictions of RNA secondary structures and computational identifications of t...
Hiroshi Matsui, Kengo Sato, Yasubumi Sakakibara
BMCBI
2006
82views more  BMCBI 2006»
13 years 7 months ago
Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
Xiaochen Bo, Shaoke Lou, Daochun Sun, Wenjie Shu, ...
BMCBI
2006
125views more  BMCBI 2006»
13 years 7 months ago
Automated functional classification of experimental and predicted protein structures
Background: Proteins that are similar in sequence or structure may perform different functions in nature. In such cases, function cannot be inferred from sequence or structural si...
Kai Wang, Ram Samudrala
BMCBI
2008
168views more  BMCBI 2008»
13 years 7 months ago
Predicting protein folding pathways at the mesoscopic level based on native interactions between secondary structure elements
Background: Since experimental determination of protein folding pathways remains difficult, computational techniques are often used to simulate protein folding. Most current techn...
Qingwu Yang, Sing-Hoi Sze
BMCBI
2008
130views more  BMCBI 2008»
13 years 7 months ago
Structural descriptor database: a new tool for sequence-based functional site prediction
Background: The Structural Descriptor Database (SDDB) is a web-based tool that predicts the function of proteins and functional site positions based on the structural properties o...
Juliana S. Bernardes, Jorge H. Fernandez, Ana Tere...