Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
: Carbon Labeling Systems (CLS) are large equation systems that describe the dynamics of labeled carbon atoms in a metabolic network. The rapid solution of these systems is the alg...
Nicole Isermann, Michael Weitzel, Wolfgang Wiecher...
Conventional Difference of Gaussian (DOG) filter is usually used to model the early stage of visual processing. However, convolution operation used with DOG does not explicitly a...
Abstract—This paper presents a stochastic modelling framework for complex biochemical reaction networks from a component-based perspective. Our approach takes into account the di...
Mila E. Majster-Cederbaum, Nils Semmelrock, Verena...
Background: The availability of complete genomic sequences for hundreds of organisms promises to make obtaining genome-wide estimates of substitution rates, selective constraints ...
Amy Egan, Anup Mahurkar, Jonathan Crabtree, Jonath...