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BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
13 years 7 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
WILF
2005
Springer
194views Fuzzy Logic» more  WILF 2005»
14 years 1 months ago
Learning Bayesian Classifiers from Gene-Expression MicroArray Data
Computing methods that allow the efficient and accurate processing of experimentally gathered data play a crucial role in biological research. The aim of this paper is to present a...
Andrea Bosin, Nicoletta Dessì, Diego Libera...
BMCBI
2005
152views more  BMCBI 2005»
13 years 7 months ago
GeneKeyDB: A lightweight, gene-centric, relational database to support data mining environments
Background: The analysis of biological data is greatly enhanced by existing or emerging databases. Most existing databases, with few exceptions are not designed to easily support ...
S. A. Kirov, X. Peng, E. Baker, D. Schmoyer, B. Zh...
AB
2008
Springer
14 years 2 months ago
An Algorithm for Qualitative Simulation of Gene Regulatory Networks with Steep Sigmoidal Response Functions
A specific class of ODEs has been shown to be adequate to describe the essential features of the complex dynamics of Gene-Regulatory Networks (GRN). But, the effective exploitatio...
Liliana Ironi, Luigi Panzeri, Erik Plahte
GECCO
2006
Springer
165views Optimization» more  GECCO 2006»
13 years 11 months ago
Comparing mathematical models on the problem of network inference
In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of different mathemat...
Christian Spieth, Nadine Hassis, Felix Streichert