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BMCBI
2005
115views more  BMCBI 2005»
13 years 7 months ago
Statistical distributions of optimal global alignment scores of random protein sequences
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
Hongxia Pang, Jiaowei Tang, Su-Shing Chen, Shiheng...
BMCBI
2005
131views more  BMCBI 2005»
13 years 7 months ago
Regularized Least Squares Cancer Classifiers from DNA microarray data
Background: The advent of the technology of DNA microarrays constitutes an epochal change in the classification and discovery of different types of cancer because the information ...
Nicola Ancona, Rosalia Maglietta, Annarita D'Addab...
JSYML
2007
100views more  JSYML 2007»
13 years 7 months ago
Combinatorial principles weaker than Ramsey's Theorem for pairs
We investigate the complexity of various combinatorial theorems about linear and partial orders, from the points of view of computability theory and reverse mathematics. We focus ...
Denis R. Hirschfeldt, Richard A. Shore
BMCBI
2004
125views more  BMCBI 2004»
13 years 7 months ago
A functional hierarchical organization of the protein sequence space
Background: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patte...
Noam Kaplan, Moriah Friedlich, Menachem Fromer, Mi...
COMPLEXITY
2004
165views more  COMPLEXITY 2004»
13 years 7 months ago
Sex promotes gamete selection: A quantitative comparative study of features favoring the evolution of sex
: Explaining the maintenance of sexual reproduction remains one of the greatest challenges in biology. The theoretical oddity of sex is based on at least three advantages that asex...
Klaus Jaffe
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