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BMCBI
2008
138views more  BMCBI 2008»
13 years 7 months ago
Application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote ho
Background: Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This uniqu...
Inkyung Jung, Jaehyung Lee, Soo-Young Lee, Dongsup...
BIBM
2007
IEEE
132views Bioinformatics» more  BIBM 2007»
14 years 1 months ago
A Divide-and-Conquer Implementation of Three Sequence Alignment and Ancestor Inference
In this paper, we present an algorithm to simultaneously align three biological sequences with affine gap model and infer their common ancestral sequence. Our algorithm can be fu...
Feng Yue, Jijun Tang
BMCBI
2006
172views more  BMCBI 2006»
13 years 7 months ago
Prediction of cis/trans isomerization in proteins using PSI-BLAST profiles and secondary structure information
Background: The majority of peptide bonds in proteins are found to occur in the trans conformation. However, for proline residues, a considerable fraction of Prolyl peptide bonds ...
Jiangning Song, Kevin Burrage, Zheng Yuan, Thomas ...
IPPS
2008
IEEE
14 years 1 months ago
SWAMP: Smith-Waterman using associative massive parallelism
One of the most commonly used tools by computational biologists is some form of sequence alignment. Heuristic alignment algorithms developed for speed and their multiple results s...
Shannon Steinfadt, Johnnie W. Baker
ISHPC
2003
Springer
14 years 20 days ago
Performance Study of a Whole Genome Comparison Tool on a Hyper-Threading Multiprocessor
We developed a multithreaded parallel implementation of a sequence alignment algorithm that is able to align whole genomes with reliable output and reasonable cost. This paper pres...
Juan del Cuvillo, Xinmin Tian, Guang R. Gao, Milin...