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ENTCS
2008
92views more  ENTCS 2008»
13 years 7 months ago
A Process Model of Rho GTP-binding Proteins in the Context of Phagocytosis
At the early stages of the phagocytic signalling, Rho GTP-binding proteins play a key role. With the stimulus from the cell membrane and with the help from the regulators (GEF, GA...
Luca Cardelli, Philippa Gardner, Ozan Kahramanogul...
ISMB
1997
13 years 9 months ago
Identifying Chimerism in Proteins Using Hidden Markov Models of Codon Usage
Protein chimerism is a phenomenon involving the combination of multiple ancestral sequences into a single, multi-domain protein through evolution. We propose a novel method for de...
Lawrence Hunter, Barry Zeeberg
ICML
2006
IEEE
14 years 8 months ago
A graphical model for predicting protein molecular function
We present a simple statistical model of molecular function evolution to predict protein function. The model description encodes general knowledge of how molecular function evolve...
Barbara E. Engelhardt, Michael I. Jordan, Steven E...
BIBM
2008
IEEE
145views Bioinformatics» more  BIBM 2008»
14 years 2 months ago
Identifying Interface Elements Implied in Protein-Protein Interactions Using Statistical Tests and Frequent Item Sets
Understanding what are the characteristics of proteinprotein interfaces is at the core of numerous applications. This paper introduces a method in which the proteins are described...
Christine Martin, Antoine Cornuéjols
BIBE
2007
IEEE
147views Bioinformatics» more  BIBE 2007»
14 years 1 months ago
A New Alignment-Independent Algorithm for Clustering Protein Sequences
—The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important, the challenge is to identify subfamilies of evolut...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski