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JCB
2006
144views more  JCB 2006»
13 years 9 months ago
Modeling Virus Self-Assembly Pathways: Avoiding Dynamics Using Geometric Constraint Decomposition
We develop a model for elucidating the assembly pathways by which an icosahedral viral shell forms from 60 identical constituent protein monomers. This poorly understood process a...
Meera Sitharam, Mavis Agbandje-Mckenna
TCBB
2011
13 years 4 months ago
A Partial Set Covering Model for Protein Mixture Identification Using Mass Spectrometry Data
—Protein identification is a key and essential step in mass spectrometry (MS) based proteome research. To date, there are many protein identification strategies that employ eithe...
Zengyou He, Can Yang, Weichuan Yu
CORR
2002
Springer
110views Education» more  CORR 2002»
13 years 9 months ago
Long Proteins with Unique Optimal Foldings in the H-P Model
It is widely accepted that (1) the natural or folded state of proteins is a global energy minimum, and (2) in most cases proteins fold to a unique state determined by their amino ...
Oswin Aichholzer, David Bremner, Erik D. Demaine, ...
PKDD
2007
Springer
76views Data Mining» more  PKDD 2007»
14 years 3 months ago
Finding Transport Proteins in a General Protein Database
The number of specialized databases in molecular biology is growing fast, as is the availability of molecular data. These trends necessitate the development of automatic methods fo...
Sanmay Das, Milton H. Saier Jr., Charles Elkan
BMCBI
2006
161views more  BMCBI 2006»
13 years 9 months ago
A novel approach to phylogenetic tree construction using stochastic optimization and clustering
Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational bi...
Ling Qin, Yixin Chen, Yi Pan, Ling Chen