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BIOCOMP
2010
13 years 6 months ago
A Model Reduction Technique for Stochastic Biochemical Kinetics
Abstract-- Modeling the intermolecular reactions in a single cell is a critical problem in computational biology. Biochemical reaction systems often involve species in both low and...
Silvana Ilie, Ekaterina Kudashkina
BMCBI
2006
239views more  BMCBI 2006»
13 years 8 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
ICTAI
2010
IEEE
13 years 6 months ago
The BioASP Library: ASP Solutions for Systems Biology
Abstract--Today's molecular biology is confronted with enormous amounts of data, generated by new high-throughput technologies, along with an increasing number of biological m...
Martin Gebser, Arne König, Torsten Schaub, Sv...
RECOMB
2005
Springer
14 years 8 months ago
The Factor Graph Network Model for Biological Systems
Abstract. We introduce an extended computational framework for studying biological systems. Our approach combines formalization of existing qualitative models that are in wide but ...
Irit Gat-Viks, Amos Tanay, Daniela Raijman, Ron Sh...
EVOW
2007
Springer
14 years 2 months ago
Modeling the Shoot Apical Meristem in A. thaliana : Parameter Estimation for Spatial Pattern Formation
Understanding the self-regulatory mechanisms controlling the spatial and temporal structure of multicellular organisms represents one of the major challenges in molecular biology. ...
Tim Hohm, Eckart Zitzler