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BMCBI
2010
112views more  BMCBI 2010»
13 years 10 months ago
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
Andrew J. Bordner
BMCBI
2010
153views more  BMCBI 2010»
13 years 10 months ago
Automatic symptom name normalization in clinical records of traditional Chinese medicine
Background: In recent years, Data Mining technology has been applied more than ever before in the field of traditional Chinese medicine (TCM) to discover regularities from the exp...
Yaqiang Wang, Zhonghua Yu, Yongguang Jiang, Kaikuo...
BMCBI
2010
147views more  BMCBI 2010»
13 years 10 months ago
CNstream: A method for the identification and genotyping of copy number polymorphisms using Illumina microarrays
Background: Understanding the genetic basis of disease risk in depth requires an exhaustive knowledge of the types of genetic variation. Very recently, Copy Number Variants (CNVs)...
Arnald Alonso, Antonio Julià, Raül Tor...
BMCBI
2010
129views more  BMCBI 2010»
13 years 10 months ago
Automatic prediction of catalytic residues by modeling residue structural neighborhood
Background: Prediction of catalytic residues is a major step in characterizing the function of enzymes. In its simpler formulation, the problem can be cast into a binary classific...
Elisa Cilia, Andrea Passerini
BMCBI
2010
87views more  BMCBI 2010»
13 years 10 months ago
Prodigal: prokaryotic gene recognition and translation initiation site identification
Background: The quality of automated gene prediction in microbial organisms has improved steadily over the past decade, but there is still room for improvement. Increasing the num...
Doug Hyatt, Gwo-Liang Chen, Philip F. LoCascio, Mi...
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