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» Active Clustering of Biological Sequences
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NAR
1998
150views more  NAR 1998»
13 years 7 months ago
PROMISE: a database of information on prosthetic centres and metal ions in protein active sites
The PROMISE (Prosthetic centres and metal ions in protein active sites) database aims to gather together comprehensive sequence, structural, functional and bibliographic informati...
Kirill Degtyarenko, A. C. North, D. N. Perkins, Jo...
BMCBI
2010
87views more  BMCBI 2010»
13 years 7 months ago
Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
Jessica L. Larson, Guo-Cheng Yuan
KDD
2006
ACM
156views Data Mining» more  KDD 2006»
14 years 8 months ago
Discovering significant OPSM subspace clusters in massive gene expression data
Order-preserving submatrixes (OPSMs) have been accepted as a biologically meaningful subspace cluster model, capturing the general tendency of gene expressions across a subset of ...
Byron J. Gao, Obi L. Griffith, Martin Ester, Steve...
IJSI
2008
122views more  IJSI 2008»
13 years 7 months ago
Mining Gene Expression Data using Domain Knowledge
Biology is now an information-intensive science and various research areas, like molecular biology, evolutionary biology or environmental biology, heavily depend on the availabilit...
Nicolas Pasquier, Claude Pasquier, Laurent Brisson...
BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
13 years 7 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li