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BMCBI
2010
117views more  BMCBI 2010»
13 years 10 months ago
Identification of NAD interacting residues in proteins
Background: Small molecular cofactors or ligands play a crucial role in the proper functioning of cells. Accurate annotation of their target proteins and binding sites is required...
Hifzur Rahman Ansari, Gajendra P. S. Raghava
BMCBI
2010
82views more  BMCBI 2010»
13 years 10 months ago
Genome-wide estimation of firing efficiencies of origins of DNA replication from time-course copy number variation data
Background: DNA replication is a fundamental biological process during S phase of cell division. It is initiated from several hundreds of origins along whole chromosome with diffe...
Huaien Luo, Juntao Li, Majid Eshaghi, Jianhua Liu,...
BMCBI
2010
118views more  BMCBI 2010»
13 years 10 months ago
Bacillus anthracis genome organization in light of whole transcriptome sequencing
Emerging knowledge of whole prokaryotic transcriptomes could validate a number of theoretical concepts introduced in the early days of genomics. What are the rules connecting gene...
Jeffrey Martin, Wenhan Zhu, Karla D. Passalacqua, ...
BMCBI
2008
155views more  BMCBI 2008»
13 years 10 months ago
Prediction of regulatory elements in mammalian genomes using chromatin signatures
Background: Recent genomic scale survey of epigenetic states in the mammalian genomes has shown that promoters and enhancers are correlated with distinct chromatin signatures, pro...
Kyoung-Jae Won, Iouri Chepelev, Bing Ren, Wei Wang
BMCBI
2008
138views more  BMCBI 2008»
13 years 10 months ago
Information transfer in signaling pathways: A study using coupled simulated and experimental data
Background: The topology of signaling cascades has been studied in quite some detail. However, how information is processed exactly is still relatively unknown. Since quite divers...
Jürgen Pahle, Anne K. Green, C. Jane Dixon, U...