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BMCBI
2004
140views more  BMCBI 2004»
13 years 7 months ago
What can we learn from noncoding regions of similarity between genomes?
Background: In addition to known protein-coding genes, large amounts of apparently non-coding sequence are conserved between the human and mouse genomes. It seems reasonable to as...
Thomas A. Down, Tim J. P. Hubbard
JMLR
2006
132views more  JMLR 2006»
13 years 8 months ago
Learning to Detect and Classify Malicious Executables in the Wild
We describe the use of machine learning and data mining to detect and classify malicious executables as they appear in the wild. We gathered 1,971 benign and 1,651 malicious execu...
Jeremy Z. Kolter, Marcus A. Maloof
IJCNN
2008
IEEE
14 years 2 months ago
A neural network approach to ordinal regression
— Ordinal regression is an important type of learning, which has properties of both classification and regression. Here we describe an effective approach to adapt a traditional ...
Jianlin Cheng, Zheng Wang, Gianluca Pollastri
BMCBI
2008
100views more  BMCBI 2008»
13 years 8 months ago
Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen p
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...
Guanglan Zhang, Asif M. Khan, Kellathur N. Sriniva...
BMCBI
2010
227views more  BMCBI 2010»
13 years 8 months ago
Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
Majid Masso, Iosif I. Vaisman