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BMCBI
2008
200views more  BMCBI 2008»
13 years 7 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
BMCBI
2008
122views more  BMCBI 2008»
13 years 7 months ago
High-throughput bioinformatics with the Cyrille2 pipeline system
Background: Modern omics research involves the application of high-throughput technologies that generate vast volumes of data. These data need to be pre-processed, analyzed and in...
Mark W. E. J. Fiers, Ate van der Burgt, Erwin Date...
BMCBI
2006
116views more  BMCBI 2006»
13 years 7 months ago
Whole genome association mapping by incompatibilities and local perfect phylogenies
Background: With current technology, vast amounts of data can be cheaply and efficiently produced in association studies, and to prevent data analysis to become the bottleneck of ...
Thomas Mailund, Søren Besenbacher, Mikkel H...
BMCBI
2006
117views more  BMCBI 2006»
13 years 7 months ago
G-InforBIO: integrated system for microbial genomics
Background: Genome databases contain diverse kinds of information, including gene annotations and nucleotide and amino acid sequences. It is not easy to integrate such information...
Naoto Tanaka, Takashi Abe, Satoru Miyazaki, Hideak...
BMCBI
2006
82views more  BMCBI 2006»
13 years 7 months ago
Prediction of a key role of motifs binding E2F and NR2F in down-regulation of numerous genes during the development of the mouse
Background: We previously demonstrated that gene expression profiles during neuronal differentiation in vitro and hippocampal development in vivo were very similar, due to a conse...
Michal Dabrowski, Stein Aerts, Bozena Kaminska