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» Adaptive Modeling of Biochemical Pathways
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EUROGP
2007
Springer
14 years 1 months ago
The Holland Broadcast Language and the Modeling of Biochemical Networks
Abstract. The Broadcast Language is a programming formalism devised by Holland in 1975, which aims at improving the efficiency of Genetic Algorithms (GAs) during long-term evolutio...
James Decraene, George G. Mitchell, Barry McMullin...
SIAMSC
2008
149views more  SIAMSC 2008»
13 years 7 months ago
Adaptive Discrete Galerkin Methods Applied to the Chemical Master Equation
In systems biology, the stochastic description of biochemical reaction kinetics is increasingly being employed to model gene regulatory networks and signalling pathways. Mathematic...
Peter Deuflhard, Wilhelm Huisinga, T. Jahnke, Mich...
ISCIS
2009
Springer
14 years 2 months ago
A web-based data source for metabolomics
—With the development of improved and cost-effective technologies, it is now possible to detect thousands of metabolites in biofluids or specific organs, and reliably quantify th...
Ali Cakmak, Arun Dsouza, Richard Hanson, Gultekin ...
JCB
2006
144views more  JCB 2006»
13 years 7 months ago
Modeling Virus Self-Assembly Pathways: Avoiding Dynamics Using Geometric Constraint Decomposition
We develop a model for elucidating the assembly pathways by which an icosahedral viral shell forms from 60 identical constituent protein monomers. This poorly understood process a...
Meera Sitharam, Mavis Agbandje-Mckenna
JBI
2004
163views Bioinformatics» more  JBI 2004»
13 years 9 months ago
Artificial Chemistries and Metabolic Pathways
Metabolism can be regarded as a network of biochemical reactions, connected via their substrates and products. A metabolic pathway is thus a coordinated series of reactions, and i...
Liliana Félix, Francesc Rosselló, Ga...