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BIOINFORMATICS
2008
172views more  BIOINFORMATICS 2008»
15 years 5 months ago
Fitting a geometric graph to a protein-protein interaction network
Motivation: Finding a good network null model for protein-protein interaction (PPI) networks is a fundamental issue. Such a model would provide insights into the interplay between...
Desmond J. Higham, Marija Rasajski, Natasa Przulj
BMCBI
2008
155views more  BMCBI 2008»
15 years 5 months ago
Extending pathways based on gene lists using InterPro domain signatures
Background: High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly...
Florian Hahne, Alexander Mehrle, Dorit Arlt, Annem...
BMCBI
2008
115views more  BMCBI 2008»
15 years 5 months ago
Probe signal correction for differential methylation hybridization experiments
Background: Non-biological signal (or noise) has been the bane of microarray analysis. Hybridization effects related to probe-sequence composition and DNA dye-probe interactions h...
Dustin P. Potter, Pearlly Yan, Tim Hui-Ming Huang,...
BMCBI
2008
159views more  BMCBI 2008»
15 years 5 months ago
Multivariate hierarchical Bayesian model for differential gene expression analysis in microarray experiments
Background: Identification of differentially expressed genes is a typical objective when analyzing gene expression data. Recently, Bayesian hierarchical models have become increas...
Hongya Zhao, Kwok-Leung Chan, Lee-Ming Cheng, Hong...
CORR
2010
Springer
109views Education» more  CORR 2010»
15 years 5 months ago
Towards the Development of a Simulator for Investigating the Impact of People Management Practices on Retail Performance
Models to understand the impact of management practices on retail performance are often simplistic and assume low levels of noise and linearity. Of course, in real-life, retail op...
Peer-Olaf Siebers, Uwe Aickelin, Helen Celia, Chri...