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BMCBI
2011
13 years 2 months ago
Systematic error detection in experimental high-throughput screening
Background: High-throughput screening (HTS) is a key part of the drug discovery process during which thousands of chemical compounds are screened and their activity levels measure...
Plamen Dragiev, Robert Nadon, Vladimir Makarenkov
BMCBI
2011
13 years 2 months ago
Dr. PIAS: an integrative system for assessing the druggability of protein-protein interactions
Background: The amount of data on protein-protein interactions (PPIs) available in public databases and in the literature has rapidly expanded in recent years. PPI data can provid...
Nobuyoshi Sugaya, Toshio Furuya
CSDA
2011
13 years 2 months ago
Functional density synchronization
Estimating an overall density function from repeated observations on each of a sample of independent subjects or experimental units is of interest. An example is provided by biodem...
Zhen Zhang, Hans-Georg Müller
JAIR
2011
134views more  JAIR 2011»
13 years 2 months ago
Scaling up Heuristic Planning with Relational Decision Trees
Current evaluation functions for heuristic planning are expensive to compute. In numerous planning problems these functions provide good guidance to the solution, so they are wort...
Tomás de la Rosa, Sergio Jiménez, Ra...
TIT
2011
134views more  TIT 2011»
13 years 2 months ago
Estimating Heavy-Tail Exponents Through Max Self-Similarity
: In this paper, a novel approach to the problem of estimating the heavy–tail exponent α > 0 of a distribution is proposed. It is based on the fact that block–maxima of siz...
Stilian Stoev, George Michailidis, Murad S. Taqqu