Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
Pseudoknots are a frequent RNA structure that assumes essential roles for varied biocatalyst cell's functions. One of the most challenging fields in bioinformatics is the pre...
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
David M. A. Martin, Matthew Berriman, Geoffrey J. ...
Background: RNAmute is an interactive Java application which, given an RNA sequence, calculates the secondary structure of all single point mutations and organizes them into categ...
Background: siRNAs are small RNAs that serve as sequence determinants during the gene silencing process called RNA interference (RNAi). It is well know that siRNA efficiency is cr...