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BMCBI
2008
13 years 7 months ago
2008
Background: Modelling proteins with multiple domains is one of the central challenges in Structural Biology. Although homology modelling has successfully been applied for predicti...
BMCBI
2008
13 years 7 months ago
2008
Background: The nucleotide substitution rate matrix is a key parameter of molecular evolution. Several methods for inferring this parameter have been proposed, with different math...
ALMOB
2006
13 years 7 months ago
2006
The use of Chaos Game Representation (CGR) or its generalization, Universal Sequence Maps (USM), to describe the distribution of biological sequences has been found objectionable ...
BMCBI
2006
13 years 7 months ago
2006
Background: Does a relationship exist between a protein's evolutionary rate and its number of interactions? This relationship has been put forward many times, based on a biol...
BMCBI
2006
13 years 7 months ago
2006
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...