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BMCBI
2005
13 years 10 months ago
2005
Background: BLAST is a widely used genetic research tool for analysis of similarity between nucleotide and protein sequences. This paper presents a software application entitled &...
BMCBI
2005
13 years 10 months ago
2005
Background: Development of robust and efficient methods for analyzing and interpreting high dimension gene expression profiles continues to be a focus in computational biology. Th...
BMCBI
2005
13 years 10 months ago
2005
Background: Detection of Loss of Heterozygosity (LOH) is one of the most common molecular applications in the study of human diseases, in particular cancer. The technique is commo...
BMCBI
2005
13 years 10 months ago
2005
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
BMCBI
2005
13 years 10 months ago
2005
Background: The identification of local similarities between two protein structures can provide clues of a common function. Many different methods exist for searching for similar ...