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» Algorithmic Folding Complexity
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BIBE
2008
IEEE
142views Bioinformatics» more  BIBE 2008»
14 years 3 months ago
Optimizing performance, cost, and sensitivity in pairwise sequence search on a cluster of PlayStations
— The Smith-Waterman algorithm is a dynamic programming method for determining optimal local alignments between nucleotide or protein sequences. However, it suffers from quadrati...
Ashwin M. Aji, Wu-chun Feng
BMCBI
2008
211views more  BMCBI 2008»
13 years 9 months ago
CPSP-tools - Exact and complete algorithms for high-throughput 3D lattice protein studies
Background: The principles of protein folding and evolution pose problems of very high inherent complexity. Often these problems are tackled using simplified protein models, e.g. ...
Martin Mann, Sebastian Will, Rolf Backofen
WABI
2010
Springer
188views Bioinformatics» more  WABI 2010»
13 years 7 months ago
Prediction of RNA Secondary Structure Including Kissing Hairpin Motifs
Abstract. We present three heuristic strategies for folding RNA sequences into secondary structures including kissing hairpin motifs. The new idea is to construct a kissing hairpin...
Corinna Theis, Stefan Janssen, Robert Giegerich
ISBI
2006
IEEE
14 years 9 months ago
Use of 3-D cortical morphometry for mapping increased cortical gyrification and complexity in Williams syndrome
In this paper, we describe the use of three different shape measures -- i.e., shape index, curvedness, and L2 norm of mean curvature -- to quantify cortical gyrification and compl...
Duygu Tosun, Allan L. Reiss, Agatha D. Lee, Rebecc...
BMCBI
2004
122views more  BMCBI 2004»
13 years 8 months ago
A comprehensive comparison of comparative RNA structure prediction approaches
Background: An increasing number of researchers have released novel RNA structure analysis and prediction algorithms for comparative approaches to structure prediction. Yet, indep...
Paul P. Gardner, Robert Giegerich