The Replica Exchange method is a popular approach for studying the folding thermodynamics of small to modest size proteins in explicit solvent, since it is easily parallelized. Ho...
Maria Eleftheriou, Aleksandr Rayshubskiy, Jed W. P...
We propose an algorithm for estimating the common secondary structure, alignment, and posterior base pairing probabilities for two RNA sequences. A definition of structural align...
Arif Ozgun Harmanci, Gaurav Sharma, David H. Mathe...
In many practical engineering design problems, the form of objective function is not given explicitly in terms of design variables. Given the value of design variables, under this ...
We define new measures of sequence similarity for oligonucleotide probe design. These new measures incorporate the nearest neighbor k-stem motifs in their definition, but can be e...
Anthony J. Macula, Alexander Schliep, Morgan A. Bi...
Background: Comparative prediction of RNA structures can be used to identify functional noncoding RNAs in genomic screens. It was shown recently by Babak et al. [BMC Bioinformatic...