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» Algorithmic Thermodynamics
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IPPS
2006
IEEE
14 years 1 months ago
Parallel implementation of the replica exchange molecular dynamics algorithm on Blue Gene/L
The Replica Exchange method is a popular approach for studying the folding thermodynamics of small to modest size proteins in explicit solvent, since it is easily parallelized. Ho...
Maria Eleftheriou, Aleksandr Rayshubskiy, Jed W. P...
ICASSP
2008
IEEE
14 years 1 months ago
Probabilistic structural alignment of RNA sequences
We propose an algorithm for estimating the common secondary structure, alignment, and posterior base pairing probabilities for two RNA sequences. A definition of structural align...
Arif Ozgun Harmanci, Gaurav Sharma, David H. Mathe...
ICANN
2001
Springer
13 years 12 months ago
A Computational Intelligence Approach to Optimization with Unknown Objective Functions
In many practical engineering design problems, the form of objective function is not given explicitly in terms of design variables. Given the value of design variables, under this ...
Hirotaka Nakayama, Masao Arakawa, Rie Sasaki
JCB
2008
75views more  JCB 2008»
13 years 7 months ago
New, Improved, and Practical k-Stem Sequence Similarity Measures for Probe Design
We define new measures of sequence similarity for oligonucleotide probe design. These new measures incorporate the nearest neighbor k-stem motifs in their definition, but can be e...
Anthony J. Macula, Alexander Schliep, Morgan A. Bi...
BMCBI
2008
114views more  BMCBI 2008»
13 years 7 months ago
Dinucleotide controlled null models for comparative RNA gene prediction
Background: Comparative prediction of RNA structures can be used to identify functional noncoding RNAs in genomic screens. It was shown recently by Babak et al. [BMC Bioinformatic...
Tanja Gesell, Stefan Washietl