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BMCBI
2010
105views more  BMCBI 2010»
13 years 6 months ago
Effects of scanning sensitivity and multiple scan algorithms on microarray data quality
Background: Maximizing the utility of DNA microarray data requires optimization of data acquisition through selection of an appropriate scanner setting. To increase the amount of ...
Andrew Williams, Errol M. Thomson
BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
13 years 6 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li
CIBB
2008
13 years 8 months ago
Unsupervised Stability-Based Ensembles to Discover Reliable Structures in Complex Bio-molecular Data
The assessment of the reliability of clusters discovered in bio-molecular data is a central issue in several bioinformatics problems. Several methods based on the concept of stabil...
Alberto Bertoni, Giorgio Valentini
KES
2008
Springer
13 years 6 months ago
An Algorithm to Assess the Reliability of Hierarchical Clusters in Gene Expression Data
The validation of clusters discovered in bio-molecular data is a central issue in bioinformatics. Recently, stability-based methods have been successfully applied to the analysis o...
Roberto Avogadri, Matteo Brioschi, Francesca Ruffi...
BMCBI
2010
151views more  BMCBI 2010»
13 years 6 months ago
BABAR: an R package to simplify the normalisation of common reference design microarray-based transcriptomic datasets
Background: The development of DNA microarrays has facilitated the generation of hundreds of thousands of transcriptomic datasets. The use of a common reference microarray design ...
Mark J. Alston, John Seers, Jay C. D. Hinton, Sach...