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IDA
2005
Springer
14 years 7 days ago
Biological Cluster Validity Indices Based on the Gene Ontology
With the invention of biotechnological high throughput methods like DNA microarrays and the analysis of the resulting huge amounts of biological data, clustering algorithms gain ne...
Nora Speer, Christian Spieth, Andreas Zell
BMCBI
2006
138views more  BMCBI 2006»
13 years 6 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
BIBE
2007
IEEE
124views Bioinformatics» more  BIBE 2007»
14 years 1 months ago
Finding Cancer-Related Gene Combinations Using a Molecular Evolutionary Algorithm
—High-throughput data such as microarrays make it possible to investigate the molecular-level mechanism of cancer more efficiently. Computational methods boost the microarray ana...
Chan-Hoon Park, Soo-Jin Kim, Sun Kim, Dong-Yeon Ch...
PR
2006
116views more  PR 2006»
13 years 6 months ago
Shared farthest neighbor approach to clustering of high dimensionality, low cardinality data
Clustering algorithms are routinely used in biomedical disciplines, and are a basic tool in bioinformatics. Depending on the task at hand, there are two most popular options, the ...
Stefano Rovetta, Francesco Masulli
IDEAL
2004
Springer
14 years 3 days ago
Visualisation of Distributions and Clusters Using ViSOMs on Gene Expression Data
Microarray datasets are often too large to visualise due to the high dimensionality. The self-organising map has been found useful to analyse massive complex datasets. It can be us...
Swapna Sarvesvaran, Hujun Yin