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BMCBI
2010
104views more  BMCBI 2010»
13 years 7 months ago
A novel scoring function for discriminating hyperthermophilic and mesophilic proteins with application to predicting relative th
Background: The ability to design thermostable proteins is theoretically important and practically useful. Robust and accurate algorithms, however, remain elusive. One critical pr...
Yunqi Li, C. Russell Middaugh, Jianwen Fang
BMCBI
2010
108views more  BMCBI 2010»
13 years 7 months ago
Predicting changes in protein thermostability brought about by single- or multi-site mutations
Background: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostabilit...
Jian Tian, Ningfeng Wu, Xiaoyu Chu, Yunliu Fan
KDD
2010
ACM
199views Data Mining» more  KDD 2010»
13 years 11 months ago
Overlapping experiment infrastructure: more, better, faster experimentation
At Google, experimentation is practically a mantra; we evaluate almost every change that potentially affects what our users experience. Such changes include not only obvious user-...
Diane Tang, Ashish Agarwal, Deirdre O'Brien, Mike ...
COCO
2001
Springer
149views Algorithms» more  COCO 2001»
14 years 2 days ago
Quantum versus Classical Learnability
Motivated by recent work on quantum black-box query complexity, we consider quantum versions of two wellstudied models of learning Boolean functions: Angluin’s model of exact le...
Rocco A. Servedio, Steven J. Gortler
ISBI
2011
IEEE
12 years 11 months ago
Boosting power to detect genetic associations in imaging using multi-locus, genome-wide scans and ridge regression
Most algorithms used for imaging genetics examine statistical effects of each individual genetic variant, one at a time. We developed a new approach, based on ridge regression, to...
Omid Kohannim, Derrek P. Hibar, Jason L. Stein, Ne...