Sciweavers

3877 search results - page 533 / 776
» Aligning Alignments
Sort
View
132
Voted
BMCBI
2010
123views more  BMCBI 2010»
15 years 3 months ago
A new protein binding pocket similarity measure based on comparison of clouds of atoms in 3D: application to ligand prediction
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
Brice Hoffmann, Mikhail Zaslavskiy, Jean-Philippe ...
139
Voted
BMCBI
2010
129views more  BMCBI 2010»
15 years 3 months ago
Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
Mindaugas Margelevicius, Ceslovas Venclovas
146
Voted
BMCBI
2010
218views more  BMCBI 2010»
15 years 3 months ago
Fast multi-core based multimodal registration of 2D cross-sections and 3D datasets
Background: Solving bioinformatics tasks often requires extensive computational power. Recent trends in processor architecture combine multiple cores into a single chip to improve...
Michael Scharfe, Rainer Pielot, Falk Schreiber
140
Voted
BMCBI
2008
87views more  BMCBI 2008»
15 years 3 months ago
Protein structure search and local structure characterization
Background: Structural similarities among proteins can provide valuable insight into their functional mechanisms and relationships. As the number of available three-dimensional (3...
Shih-Yen Ku, Yuh-Jyh Hu
121
Voted
BMCBI
2010
142views more  BMCBI 2010»
15 years 3 months ago
Classification of protein sequences by means of irredundant patterns
Background: The classification of protein sequences using string algorithms provides valuable insights for protein function prediction. Several methods, based on a variety of diff...
Matteo Comin, Davide Verzotto