Background: Bisulfite sequencing using next generation sequencers yields genome-wide measurements of DNA methylation at single nucleotide resolution. Traditional aligners are not ...
We construct finite groups whose Cayley graphs have large girth even w.r.t. a discounted distance measure that contracts arbitrarily long sequences of edges from the same colour ...
The use of sequence alignments for establishing protein homology relationships has an extensive tradition in the field of bioinformatics, and there is an increasing desire for more...
Public computing can potentially supply not only computational power but also memory and short term storage resources to grid and cluster scale problems. Gene sequence alignment i...
Abstract. In this paper we propose a chaining method that can align a draft genomic sequence against a finished genome. We introduce the use of an overlap tree to enhance the state...
Mukund Sundararajan, Michael Brudno, Kerrin Small,...