391 search results - page 58 / 79 » Aligning Two Fragmented Sequences |
BMCBI
2006
13 years 10 months ago
2006
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
BMCBI
2005
13 years 9 months ago
2005
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
BMCBI
2008
13 years 10 months ago
2008
Background: Array-based comparative genome hybridization (aCGH) is commonly used to determine the genomic content of bacterial strains. Since prokaryotes in general have less cons...
BMCBI
2010
13 years 10 months ago
2010
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
BMCBI
2008
13 years 10 months ago
2008
Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...