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» Aligning Two Fragmented Sequences
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BMCBI
2010
95views more  BMCBI 2010»
13 years 10 months ago
An effective approach for identification of in vivo protein-DNA binding sites from paired-end ChIP-Seq data
Background: ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of prot...
Congmao Wang, Jie Xu, Dasheng Zhang, Zoe A. Wilson...
BMCBI
2010
154views more  BMCBI 2010»
13 years 10 months ago
An algorithm for automated closure during assembly
Background: Finishing is the process of improving the quality and utility of draft genome sequences generated by shotgun sequencing and computational assembly. Finishing can invol...
Sergey Koren, Jason R. Miller, Brian Walenz, Grang...
BMCBI
2011
13 years 5 months ago
RAIphy: Phylogenetic classification of metagenomics samples using iterative refinement of relative abundance index profiles
Background: Computational analysis of metagenomes requires the taxonomical assignment of the genome contigs assembled from DNA reads of environmental samples. Because of the diver...
Ozkan U. Nalbantoglu, Samuel F. Way, Steven H. Hin...
SIGDIAL
2010
13 years 7 months ago
Comparing Local and Sequential Models for Statistical Incremental Natural Language Understanding
Incremental natural language understanding is the task of assigning semantic representations to successively larger prefixes of utterances. We compare two types of statistical mod...
Silvan Heintze, Timo Baumann, David Schlangen
BMCBI
2010
163views more  BMCBI 2010»
13 years 10 months ago
Reduced representation of protein structure: implications on efficiency and scope of detection of structural similarity
Background: Computational comparison of two protein structures is the starting point of many methods that build on existing knowledge, such as structure modeling (including modeli...
Zong Hong Zhang, Hwee Kuan Lee, Ivana Mihalek