Background: Two central problems in computational biology are the determination of the alignment and phylogeny of a set of biological sequences. The traditional approach to this p...
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
Through clean-slate implementation of two storage optimizations--track-aligned extents and track-aligned RAIDs--this paper shows the values of independent validations. The experie...