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BMCBI
2005
75views more  BMCBI 2005»
13 years 8 months ago
Prediction of a common structural scaffold for proteasome lid, COP9-signalosome and eIF3 complexes
Background: The 'lid' subcomplex of the 26S proteasome and the COP9 signalosome (CSN complex) share a common architecture consisting of six subunits harbouring a so-call...
Hartmut Scheel, Kay Hofmann
BMCBI
2005
67views more  BMCBI 2005»
13 years 8 months ago
Sequence signature analysis of chromosome identity in three Drosophila species
Background: All eukaryotic organisms need to distinguish each of their chromosomes. A few protein complexes have been described that recognise entire, specific chromosomes, for in...
Per Stenberg, Fredrik Pettersson, Anja O. Saura, A...
BMCBI
2005
152views more  BMCBI 2005»
13 years 8 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
BMCBI
2005
147views more  BMCBI 2005»
13 years 8 months ago
Calibration of mass spectrometric peptide mass fingerprint data without specific external or internal calibrants
Background: Peptide Mass Fingerprinting (PMF) is a widely used mass spectrometry (MS) method of analysis of proteins and peptides. It relies on the comparison between experimental...
Witold E. Wolski, Maciej Lalowski, Peter Jungblut,...
BMCBI
2005
73views more  BMCBI 2005»
13 years 8 months ago
Evaluation of Glycine max mRNA clusters
Background: Clustering the ESTs from a large dataset representing a single species is a convenient starting point for a number of investigations into gene discovery, genome evolut...
Ronald L. Frank, Fikret Erçal