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» Alignment of Non-Overlapping Sequences
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BMCBI
2006
134views more  BMCBI 2006»
13 years 10 months ago
A statistical score for assessing the quality of multiple sequence alignments
Background: Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein...
Virpi Ahola, Tero Aittokallio, Mauno Vihinen, Esa ...
BMCBI
2005
122views more  BMCBI 2005»
13 years 10 months ago
Bayesian coestimation of phylogeny and sequence alignment
Background: Two central problems in computational biology are the determination of the alignment and phylogeny of a set of biological sequences. The traditional approach to this p...
Gerton Lunter, István Miklós, Alexei...
AINA
2006
IEEE
14 years 4 months ago
Partitioned optimization algorithms for multiple sequence alignment
Multiple sequence alignment is an important and difficult problem in molecular biology and bioinformatics. In this paper, we propose a partitioning approach that significantly impr...
Yixin Chen, Yi Pan, Juan Chen, Wei Liu, Ling Chen