Background: Sequence comparisons make use of a one-letter representation for amino acids, the necessary quantitative information being supplied by the substitution matrices. This ...
Background: Ultraconserved elements are nucleotide or protein sequences with 100% identity (no mismatches, insertions, or deletions) in the same organism or between two or more or...
Background: Publicly accessible EST libraries contain valuable information that can be utilized for studies of tissue-specific gene expression and processing of individual genes. ...
Background: A new sequence independent bioinformatics approach allowing genome-wide search for proteins with similar three dimensional structures has been developed. By utilizing ...
Uncertainty handling plays an important role during shape tracking. We have recently shown that the fusion of measurement information with system dynamics and shape priors greatly...
Xiang Sean Zhou, Dorin Comaniciu, Binglong Xie, R....