DNA sequence alignment is a critical step in identifying homology between organisms. The most widely used alignment program, ClustalW, is known to suffer from the local minima pro...
Perry Ridge, Hyrum Carroll, Dan Sneddon, Mark J. C...
Background: The dynamic motions of many proteins are central to their function. It therefore follows that the dynamic requirements of a protein are evolutionary constrained. In or...
Background: The Smith-Waterman algorithm for local sequence alignment is more sensitive than heuristic methods for database searching, but also more time-consuming. The fastest ap...
Abstract. Multiple sequence alignment is a key process in today’s biology, and finding a relevant alignment of several sequences is much more challenging than just optimizing so...
Sequence Alignment is a basic information disposal method in Bioinformatics. However, it is difficult to deal with multiple sequence alignment problem(MSA). In this paper, an impro...