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» Alignment of Polarized Sets
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ICFP
2010
ACM
15 years 5 months ago
Matching lenses: alignment and view update
Bidirectional programming languages are a practical approach to the view update problem. Programs in these languages, called lenses, define both a view and an update policy--i.e.,...
Davi M. J. Barbosa, Julien Cretin, Nate Foster, Mi...
ALMOB
2007
151views more  ALMOB 2007»
15 years 4 months ago
Local sequence alignments statistics: deviations from Gumbel statistics in the rare-event tail
Background: The optimal score for ungapped local alignments of infinitely long random sequences is known to follow a Gumbel extreme value distribution. Less is known about the imp...
Stefan Wolfsheimer, Bernd Burghardt, Alexander K. ...
BMCBI
2005
109views more  BMCBI 2005»
15 years 4 months ago
Genome comparison without alignment using shortest unique substrings
Background: Sequence comparison by alignment is a fundamental tool of molecular biology. In this paper we show how a number of sequence comparison tasks, including the detection o...
Bernhard Haubold, Nora Pierstorff, Friedrich M&oum...
BMCBI
2004
154views more  BMCBI 2004»
15 years 4 months ago
Base-By-Base: Single nucleotide-level analysis of whole viral genome alignments
Background: With ever increasing numbers of closely related virus genomes being sequenced, it has become desirable to be able to compare two genomes at a level more detailed than ...
Ryan Brodie, Alex J. Smith, Rachel L. Roper, Vasil...
RECOMB
2005
Springer
16 years 4 months ago
Pairwise Local Alignment of Protein Interaction Networks Guided by Models of Evolution
Abstract. With ever increasing amount of available data on protein-protein interaction (PPI) networks and research revealing that these networks evolve at a modular level, discover...
Mehmet Koyutürk, Ananth Grama, Wojciech Szpan...