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» Alignments of RNA Structures
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BMCBI
2010
129views more  BMCBI 2010»
13 years 7 months ago
The LabelHash Algorithm for Substructure Matching
Background: There is an increasing number of proteins with known structure but unknown function. Determining their function would have a significant impact on understanding diseas...
Mark Moll, Drew H. Bryant, Lydia E. Kavraki
BMCBI
2008
130views more  BMCBI 2008»
13 years 7 months ago
An enhanced partial order curve comparison algorithm and its application to analyzing protein folding trajectories
Background: Understanding how proteins fold is essential to our quest in discovering how life works at the molecular level. Current computation power enables researchers to produc...
Hong Sun, Hakan Ferhatosmanoglu, Motonori Ota, Yus...
BMCBI
2008
144views more  BMCBI 2008»
13 years 7 months ago
Pep-3D-Search: a method for B-cell epitope prediction based on mimotope analysis
Background: The prediction of conformational B-cell epitopes is one of the most important goals in immunoinformatics. The solution to this problem, even if approximate, would help...
Yanxin Huang, Yongli Bao, Shu Yan Guo, Yan Wang, C...
BMCBI
2008
144views more  BMCBI 2008»
13 years 7 months ago
Rule-based knowledge aggregation for large-scale protein sequence analysis of influenza A viruses
Background: The explosive growth of biological data provides opportunities for new statistical and comparative analyses of large information sets, such as alignments comprising te...
Olivo Miotto, Tin Wee Tan, Vladimir Brusic
BMCBI
2006
160views more  BMCBI 2006»
13 years 7 months ago
Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources
Background: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons an...
Mario Stanke, Oliver Schöffmann, Burkhard Mor...