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BMCBI
2006
13 years 9 months ago
2006
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
BMCBI
2006
13 years 9 months ago
2006
Background: Designing novel proteins with site-directed recombination has enormous prospects. By locating effective recombination sites for swapping sequence parts, the probabilit...
BMCBI
2006
13 years 9 months ago
2006
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
BMCBI
2006
13 years 9 months ago
2006
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
CCE
2006
13 years 9 months ago
2006
There has been significant progress in the area of short-term scheduling of batch processes, including the solution of industrial-sized problems, in the last 20 years. The main go...