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» An Adaptive Supersampling Method
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111
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BMCBI
2008
122views more  BMCBI 2008»
15 years 3 months ago
Effects of dependence in high-dimensional multiple testing problems
Background: We consider effects of dependence among variables of high-dimensional data in multiple hypothesis testing problems, in particular the False Discovery Rate (FDR) contro...
Kyung In Kim, Mark A. van de Wiel
143
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ENTCS
2008
142views more  ENTCS 2008»
15 years 3 months ago
An Open System Operational Semantics for an Object-Oriented and Component-Based Language
Object orientation and component-based development have both proven useful for the elaboration of open distributed systems. These paradigms are offered by the Creol language. Creo...
Jasmin Christian Blanchette, Olaf Owe
154
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BMCBI
2006
179views more  BMCBI 2006»
15 years 3 months ago
Multiscale Hy3S: Hybrid stochastic simulation for supercomputers
Background: Stochastic simulation has become a useful tool to both study natural biological systems and design new synthetic ones. By capturing the intrinsic molecular fluctuation...
Howard Salis, Vassilios Sotiropoulos, Yiannis N. K...
BMCBI
2006
161views more  BMCBI 2006»
15 years 3 months ago
A novel approach to phylogenetic tree construction using stochastic optimization and clustering
Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational bi...
Ling Qin, Yixin Chen, Yi Pan, Ling Chen
148
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BMCBI
2006
132views more  BMCBI 2006»
15 years 3 months ago
Genome-wide DNA polymorphism analyses using VariScan
Background: DNA sequence polymorphisms analysis can provide valuable information on the evolutionary forces shaping nucleotide variation, and provides an insight into the function...
Stephan Hutter, Albert J. Vilella, Julio Rozas