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» An Axiomatic Approach to Link Prediction
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BMCBI
2005
201views more  BMCBI 2005»
13 years 7 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
BMCBI
2008
110views more  BMCBI 2008»
13 years 7 months ago
Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated da
Background: We have previously described an approach to predicting the substrate specificity of serine-threonine protein kinases. The method, named Predikin, identifies key conser...
Neil F. W. Saunders, Ross I. Brinkworth, Thomas Hu...
BMCBI
2004
153views more  BMCBI 2004»
13 years 7 months ago
Computational protein biomarker prediction: a case study for prostate cancer
Background: Recent technological advances in mass spectrometry pose challenges in computational mathematics and statistics to process the mass spectral data into predictive models...
Michael Wagner, Dayanand N. Naik, Alex Pothen, Sri...
BIBM
2010
IEEE
158views Bioinformatics» more  BIBM 2010»
13 years 5 months ago
Protein-protein interaction prediction via Collective Matrix Factorization
Abstract--Protein-protein interactions (PPI) play an important role in cellular processes and metabolic processes within a cell. An important task is to determine the existence of ...
Qian Xu, Evan Wei Xiang, Qiang Yang
RSCTC
2000
Springer
197views Fuzzy Logic» more  RSCTC 2000»
13 years 11 months ago
Rough Set Approach to CBR
We discuss how Case Based Reasoning (CBR) (see e.g. [1], [4]) philosophy of adaptation of some known situations to new similar ones can be realized in rough set framework [5] for c...
Jan Wierzbicki