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BMCBI
2011
13 years 2 months ago
Worm Phenotype Ontology: integrating phenotype data within and beyond the C. elegans community
Background: Caenorhabditis elegans gene-based phenotype information dates back to the 1970’s, beginning with Sydney Brenner and the characterization of behavioral and morphologi...
Gary Schindelman, Jolene Fernandes, Carol Bastiani...
BMCBI
2005
135views more  BMCBI 2005»
13 years 7 months ago
A robust two-way semi-linear model for normalization of cDNA microarray data
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...
BMCBI
2010
97views more  BMCBI 2010»
13 years 5 months ago
Preprocessing of gene expression data by optimally robust estimators
Background: The preprocessing of gene expression data obtained from several platforms routinely includes the aggregation of multiple raw signal intensities to one expression value...
Matthias Kohl, Hans-Peter Deigner
BMCBI
2005
155views more  BMCBI 2005»
13 years 7 months ago
Mining protein function from text using term-based support vector machines
Background: Text mining has spurred huge interest in the domain of biology. The goal of the BioCreAtIvE exercise was to evaluate the performance of current text mining systems. We...
Simon B. Rice, Goran Nenadic, Benjamin J. Stapley
BMCBI
2005
126views more  BMCBI 2005»
13 years 7 months ago
Integrative analysis of multiple gene expression profiles with quality-adjusted effect size models
Background: With the explosion of microarray studies, an enormous amount of data is being produced. Systematic integration of gene expression data from different sources increases...
Pingzhao Hu, Celia M. T. Greenwood, Joseph Beyene