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BMCBI
2010
86views more  BMCBI 2010»
15 years 6 months ago
A novel approach to simulate gene-environment interactions in complex diseases
Background: Complex diseases are multifactorial traits caused by both genetic and environmental factors. They represent the major part of human diseases and include those with lar...
Roberto Amato, Michele Pinelli, Daniel D'Andrea, G...
BMCBI
2008
122views more  BMCBI 2008»
15 years 6 months ago
A practical comparison of two K-Means clustering algorithms
Background: Data clustering is a powerful technique for identifying data with similar characteristics, such as genes with similar expression patterns. However, not all implementat...
Gregory A. Wilkin, Xiuzhen Huang
CORR
2008
Springer
173views Education» more  CORR 2008»
15 years 6 months ago
Decomposition Principles and Online Learning in Cross-Layer Optimization for Delay-Sensitive Applications
In this paper, we propose a general cross-layer optimization framework in which we explicitly consider both the heterogeneous and dynamically changing characteristics of delay-sens...
Fangwen Fu, Mihaela van der Schaar
BMCBI
2005
142views more  BMCBI 2005»
15 years 6 months ago
transAlign: using amino acids to facilitate the multiple alignment of protein-coding DNA sequences
Background: Alignments of homologous DNA sequences are crucial for comparative genomics and phylogenetic analysis. However, multiple alignment represents a computationally difficu...
Olaf R. P. Bininda-Emonds
CLUSTER
2004
IEEE
15 years 5 months ago
Towards Real-Time Fault-Tolerant CORBA Middleware
An increasing number of applications are being developed using distributed object computing (DOC) middleware, such as CORBA. Many of these applications require the underlying midd...
Aniruddha S. Gokhale, Balachandran Natarajan, Doug...