We developed Relational Data Mining approach which allows to overcome essential limitations of the Data Mining and Knowledge Discovery techniques. In the paper the approach was im...
I. V. Khomicheva, Eugenii E. Vityaev, Elena A. Ana...
Background: Many dimeric protein complexes bind cooperatively to families of bipartite nucleic acid sequence elements, which consist of pairs of conserved half-site sequences sepa...
Background: One of the challenges of bioinformatics remains the recognition of short signal sequences in genomic DNA such as donor or acceptor splice sites, splicing enhancers or ...
Jens Keilwagen, Jan Grau, Stefan Posch, Ivo Grosse
Background: Event sequences where different types of events often occur close together arise, e.g., when studying potential transcription factor binding sites (TFBS, events) of ce...
Mechanistic models for transcriptional regulation are derived using the methods of equilibrium statistical mechanics, to model equilibrating processes that occur at a fast time sc...